MEMBERS

Jiyeon Leem
Postdoctoral Scientist
E-mail
My journey as a researcher began in Integrative Biotechnology at Sungkyunkwan University and has been anchored in the realm of molecular and cellular biology. I developed a deep fascination for the intricate molecular mechanisms within cells, particularly regarding DNA damage responses and genomic integrity. In my doctoral thesis, I immersed myself in the molecular intricacies of DNA damage response and repair in mouse oocytes under the supervision of Dr. Jeong Su Oh. A pivotal achievement was identifying how DNA damage triggers response pathways during meiosis, an area with limited prior understanding. I pioneered DNA damage response and repair mechanisms, unveiling the complex interplay between chromosomes and spindle microtubules—a critical facet in maintaining genomic stability during meiosis.
Building upon my academic background and research experiences, I became intrigued by the significant role of the cytoskeleton in preserving genome integrity and its dynamic nature in supporting post-fertilization and early embryo development. This, coupled with my unwavering interest in oocyte physiology, positions me to pursue novel avenues of research in the Mogessie lab.
Now, as a member of the Mogessie lab, I am honored to advance my scientific pursuits. My current research focuses on how female reproductive aging influences chromosome segregation in mammalian oocytes and early embryo development. Driven by a deep-seated passion for investigating the physiology of oocytes, my goal is to cultivate an academic career that advances our understanding of reproductive biology.
List of publications
Unraveling the mysteries of female meiosis through quantitative cell biology